Asclera® is a sclerosing agent that is injected into the vein. It works by damaging the endothelium, the cells lining the inside of blood vessels. This causes blood platelets to attach to the lining of the vessels; eventually, cellular debris and platelets cause the blood vessel to clot. Over time, the clotted vein will be replaced with tissue.

For two to three days following the treatment, avoid:

  • Heavy exercise for 72 hours
  • Hot bath or sauna for 72 hours
  • Swimming for 72 hours
  • Sun exposure to treated area for 2-4 weeks

Severe allergic reactions have been reported following polidocanol use, including anaphylactic reactions. Severe reactions are most frequent with use of larger volumes (> 3 mL). In rare cases, formation of small “burns” or ulcers form, usually due to leakage of Asclera® into the skin. They heal in time, but may leave a scar. Inadvertent perivascular injection of Asclera® can cause discomfort.

A typical sclerotherapy session lasts 30 to 60 minutes. One injection is usually administered per inch with multiple injections per session.

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